HHV8 and Kaposi's sarcoma: a time cohort study.
نویسندگان
چکیده
منابع مشابه
Kaposis sarcoma in a Nairobi hospital.
BACKGROUND Kaposi's sarcoma (KS) is associated epidemiologically with HIV infection and a number of countries have reported a dramatic increase in the incidence of KS with the advent of AIDS. Although AIDS is prevalent in Kenya, no studies on the impact of AIDS on the pattern of KS has been carried out. OBJECTIVE To determine any changes in the pattern of KS that might have occurred since the...
متن کاملCyclin D1 expression and HHV8 in Kaposi sarcoma.
BACKGROUND Human herpesvirus 8 (HHV8) appears to be the agent responsible for Kaposi sarcoma. The mechanism remains undetermined but may involve cell cycle regulating genes including D type cyclins which are pivotal in cell cycle progression. Recent HHV8 genetic analysis has revealed the presence of a v-cyclin which is homologous to D type cyclins. AIMS First, to assess whether there is an in...
متن کاملNucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8).
The genome of the Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) was mapped with cosmid and phage genomic libraries from the BC-1 cell line. Its nucleotide sequence was determined except for a 3-kb region at the right end of the genome that was refractory to cloning. The BC-1 KSHV genome consists of a 140.5-kb-long unique coding region flanked by multiple G + C-rich 801-bp terminal repeat...
متن کاملDifferences in the frequency and function of HHV8-specific CD8 T cells between asymptomatic HHV8 infection and Kaposi sarcoma.
It is unclear how the immune response controls human herpesvirus 8 (HHV8; also known as Kaposi sarcoma-associated herpesvirus [KSHV]) replication and thereby prevents Kaposi sarcoma (KS). We compared CD8 T-cell responses to HHV8 latent (K12) and lytic (glycoprotein B, ORF6, ORF61, and ORF65) antigens in patients who spontaneously controlled the infection and in patients with posttransplantation...
متن کاملComparison of Prevalence of Kaposi’s Sarcoma in HHV8 and HHV8 HIV Infected Patients in South-South Nigeria
This study was carried out to see if there are any differences between the prevalence of Kaposi’s sarcoma in HIV infected patients with antibody to Human Herpes Virus 8 (HHV8) or not. Methods: The sera of 180 subjects were evaluated for HIV and HHV8 using double ELISA (Genscreen Ultra HIV Ag-Ab ELISA and JN HIV 1/2 ELISA Kit) for HIV screening and advanced Biotechnology Incorporated ELISA for H...
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ژورنال
عنوان ژورنال: Molecular Pathology
سال: 1997
ISSN: 1366-8714
DOI: 10.1136/mp.50.2.96